General Information

  • ID:  hor002462
  • Uniprot ID:  NA
  • Protein name:  Caerulein
  • Gene name:  NA
  • Organism:  Agalychnis callidryas
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EDYKGWMDF
  • Length:  9
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T1 Pyrrolidone carboxylic acid;T3 Tyrosine Sulfotyrosine;T9 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002462_AF2.pdbhor002462_ESM.pdb

Physical Information

Mass: 133317 Formula: C55H71N11O17S
Absent amino acids: ACHILNPQRSTV Common amino acids: D
pI: 3.88 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 2
Hydrophobicity: -136.67 Boman Index: -2134
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: 5250 Extinction Coefficient cystines: 6990
Absorbance 280nm: 873.75

Literature

  • PubMed ID:  9145422
  • Title:  Tachykinins and Other Biologically Active Peptides From the Skin of the Costa Rican Phyllomedusid Frog Agalychnis Callidryas